庚型肝炎病毒(HGV)感染在原发性肝细胞癌(HCC)发生中作用的探讨

To study the effection on the patients suffered from hepatocellular carcinoma (HCC) by the hepatitis G virus (HGV) infection, Serum HGVRNA (NS3) , anti-HGV and anti-HCV were detected by RT-PCR or ELISA in experiment group (77patients with HCC) , control group1 (56 persons with health checking annual) and control group2 (38 patients with liver cirrhosis after hepatitis ) . The Positive rate of HGVRNA was 5 2% (3/58) in experiment group, 5 3% (2/38) in control group1 and 6 7% (2/30) in control group2. P>0 05. The positive rate of anti-HGV and anti-HCV in three groupswere 25 9% (20/77) , 7 2% (4/56) and 8 3% (3/36) , P<0 01;18.1% (14/77) , 1.7% (1/56) and 2.8% (1/36) , P<0.01. The anti-HCV was detected in 12 of 27 patients with anti-HGV positive, the co-positive rate was 44.4%; while the anti-HGV was detected in 11 of 16 patients with anti-HCV positive, the co-positive rate was 68.7%. No effection have been found on the HCC by HGV infection. Anti-HCV may disturb the anti-HGV when the later is being detected by ELISA.