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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2010
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Research on the progress of CIK immunotherapy on liver cancer

  • Published Date: 2010-06-20
  • Hepatocellular carcinoma (HCC) is the second commonest cause of cancer death worldwide and the result of the conventional treatment was not as effective, so demand for the effective treatment options are increasing.Cytokine induced killer (CIK) cells are a new kind of immunocyte, which could act as antitumor with high efficiency of killer activity of T lymphocytes and the non-MHC restricted character of NK markers.Adoptive immunotherapy with CIK cells might represent an effective alternative to classic application for Hepatic carcinomas.This article reviews the new research progress on Cytokine induced killer cells, the effects of killer cells activity intervened by variety of cytokines and different pathways, the mechanisms of the killing and the pre-clinical and clinical research on cytokine-induced killer (CIK) cells.

     

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