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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 1
Jan.  2012
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Connective tissue growth factor regulates the pathogenesis of hepatic fibrosis through estrogen receptors (ER) signal transduction

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  • Published Date: 2012-01-20
  • There is significant difference between male and female in the pathogenesis of hepatic fibrosis by many clinical epidemiology's data.It was proved that estrogen played an important role through the signal transduction of estrogen receptors.Connective tissue growth factor (CTGF) was found to be related with liver fibrosis.As an important cofactors of estrogen receptor signaling, CTGF could directly regulate the pathogenesis of liver fibrosis.

     

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