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内分泌腺来源的血管内皮细胞生长因子在人胰腺癌组织中的表达及临床意义

任丽楠 郭晓钟 邹德莉

引用本文:
Citation:

内分泌腺来源的血管内皮细胞生长因子在人胰腺癌组织中的表达及临床意义

基金项目: 

国家自然科学基金(81071982); 辽宁省博士科研启动基金(20111094); 

详细信息
  • 中图分类号: R735.9

EG-VEGF expression and significance in pancreatic carcinoma

Research funding: 

 

  • 摘要: 目的探讨内分泌腺来源的血管内皮细胞生长因子(EG-VEGF)在人胰腺癌组织中的表达及临床意义。方法应用免疫组化技术检测EG-VEGF在60例胰腺癌组织和10例正常胰腺组织中的表达情况,并分析其与临床病理因素之间的关系。结果EG-VEGF在60例胰腺癌组织中的阳性表达率为95%(57/60),而在10例正常胰腺组织中的阳性表达率为10%(1/10),两者间差异有统计学意义(P<0.05)。EG-VEGF的表达与胰腺癌的临床病理分期以及淋巴结转移呈正相关(P<0.05),而与性别、年龄、病理分级无明显相关性(P>0.05)。结论 EG-VEGF在胰腺癌的发生发展过程中起着重要作用,可作为判断胰腺癌预后的有用指标。

     

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  • 出版日期:  2012-08-20
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