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肝硬化腹水伴自发性细菌性腹膜炎的诊断及治疗

吴海清 王晖

引用本文:
Citation:

肝硬化腹水伴自发性细菌性腹膜炎的诊断及治疗

基金项目: 

国家自然科学基金(No:81070334); 上海市科技发展基金(No:10411966800); 中国肝炎防治基金会王宝恩肝纤维化研究基金; 

详细信息
  • 中图分类号: R575.2

Diagnosis and treatment of spontaneous bacterial peritonitis in patients with liver ascites

Research funding: 

 

  • 摘要: <正>自发性细菌性腹膜炎(spontaneous bacterial peritonitis,SBP)是肝硬化腹水患者的一种常见而严重的并发症,指在无腹腔内邻近器官直接细菌来源(如肠穿孔、肠脓肿)的情况下发生的腹膜急性弥漫性细菌感染,感染主要源于肠道、胆道及

     

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    [2]European Association for the Study of the Liver.EASL clinicalpractice guidelines on the management of ascites, spontane-ous bacterial peritonitis, and hepatorenal syndrome in cirrho-sis[J].J Hepatol, 2010, 53 (3) :397-417.
    [3]Mounzer R, Malik SM, Nasr J, et al.Spontaneous bacterialperitonitis before liver transplantation does not affect patientsurvival[J].Clin Gastroenterol Hepatol, 2010, 8 (7) :623-628.
    [4]吴孟超, 李孟华.实用肝病学[M].第一版.北京:人民卫生出版社, 2011:510-513.
    [5]Runyon BA;AASLD Practice Guidelines Committee.Manage-ment of adult patients with ascites due to cirrhosis:an update[J].Hepatology, 2009, 49 (6) :2087-2107.
    [6]冯鑫.2010年欧洲肝脏研究协会《肝硬化腹水、自发性细菌性腹膜炎、肝肾综合征临床实践指南》简介[J].胃肠病学和肝病学杂志, 2011, 20 (3) :291-294.
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    [9]Francés R, Benlloch S, Zapater P, et al.A sequentialstudyof serum bacterial DNA in patients with advanced cirrhosisand ascites[J].Hepatology, 2004, 39 (2) :484-491.
    [10]Such J, Hillebrand DJ, Guarner C, et al.Tumor necrosis fac-torα, interleukin-6, and nitric oxide in sterile ascitic fluidand serum from patients with cirrhosis who subsequently de-velop ascitic fluid infection[J].Dig Dis Sci, 2001, 46 (11) :2360-2366.
    [11]陈银芸, 霍继荣.乙型肝炎肝硬化并发腹膜炎患者血清及腹腔积液TNF-α、IL-8、IL-18水平临床意义的探讨[J].中国当代医药, 2010, 17 (14) :32-34.
    [12] 唐能源, 陈伟庆.血清及腹水脂多糖结合蛋白检测在肝硬化自发性细菌性腹膜炎诊断中的意义[J].中华肝脏病杂志, 2012, 20 (7) :492-496.
    [13]Kuiper JJ, de Man RA, van Buuren HR.Review article:Man-agement of ascites and associated complications in patientswith cirrhosis[J].Aliment Pharmacol Ther, 2007, 26 (Suppl 2) :183-193.
    [14]Yakar T, GülüM, Serin E, et al.A recent evaluation of em-pirical cephalosporin treatment and antibiotic resistance ofchanging bacterial profiles in spontaneous bacterial peritonitis[J].Dig Dis Sci, 2010, 55 (4) :1149-1154.
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  • 出版日期:  2012-09-20
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