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丙型肝炎病毒感染及抗病毒治疗对甲状腺的影响

亓传旺 陈倩 张会 潘煜

引用本文:
Citation:

丙型肝炎病毒感染及抗病毒治疗对甲状腺的影响

详细信息
  • 中图分类号: R512.63

Effects of hepatitis C virus and antiviral treatment on thyroid function and thyroid autoantibody levels

  • 摘要:

    丙型肝炎病毒(HCV)是慢性肝炎、肝硬化、肝细胞癌的主要原因。多种肝外疾病都和HCV慢性感染有关系,并且在慢性HCV感染的患者中甲状腺失调是很普遍的。干扰素(IFN)联合利巴韦林(RBV)被公认为是治疗慢性丙型肝炎患者有效的方案,然而,甲状腺功能紊乱也是IFN抗病毒治疗的一个副作用。本综述包含了HCV慢性感染直接对甲状腺的影响和IFNα联合RBV抗病毒治疗所诱发的甲状腺功能紊乱及自身抗体的变化。

     

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