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妊娠期急性脂肪肝并发急性呼吸窘迫综合征3例报告

付菲 林影 刘晶华 张晓红

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妊娠期急性脂肪肝并发急性呼吸窘迫综合征3例报告

详细信息
  • 中图分类号: R714.25

Clinical investigation of acute fatty liver of pregnancy with acute respiratory distress syndrome: A report of 3 cases

  • 摘要:

    <正>妊娠期急性脂肪肝(acute fatty liver of pregnancy,AFLP)是一发病急剧,进展极快的妊娠晚期孕妇特有疾病[1]。其病理改变是以肝细胞脂肪变性为主要特征的多种重要器官的脂肪变性。起病急骤,病死率高,常伴有弥漫性血管内凝血(dis-seminated or diffuse intravascular coagulation,DIC)、肾功能衰竭、肝性脑病等严重并发症。急性呼吸窘迫综合征(acute re-

     

  • [1] Intensive Medical Branch of China Medical Association.Guideline formanagement of acute lung injury/acute respiratory distress syndrome:an evidence-based update by the Chinese Society of Critical CareMedicine (2006) [J].Chin J Emerg Med, 2007, 16 (4) :343-349. (in Chinese) 中华医学会重症医学分会.急性肺损伤/急性呼吸窘迫综合征诊断和治疗指南 (2006) [J].中华急诊医学杂志, 2007, 16 (4) :343-349.
    [2]Yang J, Lin F, Zhu X, et al.The influence of high positive end-expiratory pressure ventilation combined with low tidal volume onprognosis of patients with acute lung injurg/acut respiratory distresssyndrome:a meta-analysis[J].Chin Critical Care Med, 2011, 23 (1) :5-9. (in Chinese) 杨君, 刘飞, 朱曦, 等, 高呼气末正压通气结合小潮气量对急性肺损伤/急性呼吸窘迫综合征患者预后影响的荟萃分析[J].中国危重病急救医学, 2011, 23 (1) :5-9.
    [3]Huang YZ, Chen YG, Peng GD, et al.Acute fatty liver of pregnancy:clinical analysis of 20 cases[J].J Pract Obstet Gynecol, 2010, 10 (26) :767-770. (in Chinese) 黄亚珍, 陈友国, 彭根大, 等.妊娠急性脂肪肝20例临床分析[J].实用妇产科杂志, 2010, 10 (26) :767-770.
    [4]Ware LB.Pathophysiology of acute lung injury and the acute respir-atory distress syndrome[J].Semin Respir Crit Care Med, 2006, 27 (4) :337-349.
    [5]Su X, Wang L, Song Y, et al.Inhibition of inflammatory responsesby ambroxol, a mucolytic agent, in a murine model of acute lung in-jury induced by lipopolysaeeharide[J].Intensive Care Med, 2004, 30 (1) :133-140.
    [6]Plataki M, Hubmayr RD.The physical basis of ventilator inducedlung injury[J].Expert Rev Respir Med, 2010, 4 (3) :373-385.
    [7]Ware LB, Bastarche JA, Wang L.Coagulation and fibrinolysis inhuman acute lung injury-new therapeutic targets?[J].Keio JMed, 2005, 54 (3) :142-149.
    [8]Rocco PR, Dos Santos C, Pelosi P.Lung parenchyma remodeling inacute respiratory distress syndrome[J].Minerva Anestesiol, 2009, 75 (12) :730-740.
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