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求同存异,兼容并济——从国内外慢加急性肝衰竭定义的演变历程统一共识

徐曼曼 陈煜

引用本文:
Citation:

求同存异,兼容并济——从国内外慢加急性肝衰竭定义的演变历程统一共识

DOI: 10.12449/JCH241108
基金项目: 

北京市高层次公共卫生技术人才建设基金资助项目 (Discipline Leader-01-12);

北京市医院管理中心“登峰”计划专项经费资助项目 (DFL20221501)

利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:徐曼曼负责撰写论文;陈煜负责拟定写作思路,指导论文撰写并修改论文。
详细信息
    通信作者:

    陈煜, chybeyond1071@ccmu.edu.cn (ORCID: 0000-0003-1906-7486)

Unified consensus and evolution of the definition of acute-on-chronic liver failure: Seeking common ground while reserving differences

Research funding: 

Construction Project of High-level Technology Talents in Public Health (Discipline Leader-01-12);

Beijing Hospitals Authority’s Ascent Plan (DFL20221501)

  • 摘要: 在慢加急性肝衰竭(ACLF)这一概念被提出的近30年来,随着对其发病机制、诊断标准、治疗措施等各个方面研究的不断深入,来自全球范围内的相关诊疗共识指南也在不断更新,但ACLF的定义始终未得到统一,定义的不同必然会阻碍诸多治疗手段、预后评分、诊疗意见的推广应用。近年来,肝病学专家们不断提出了统一ACLF定义的方式方法,求同存异,取长补短,最终力求使ACLF的定义趋于一致。

     

  • 图  1  世界各地肝病学会发布ACLF指南或共识时间轴

    注: APASL,亚太肝病学会;CMA,中华医学会;COSSH,中国重型乙型肝炎研究小组;EASL,欧洲肝病学会;NACSELD,北美终末期肝病学会。

    Figure  1.  Liver societies around the world publish ACLF guidelines or consensus timelines

    图  2  为统一ACLF定义,世界各地学会及学者的建议

    注: ACG,美国胃肠病学院;AASLD,美国肝病学会;WGO,世界胃肠病学组织;CGSLD,中国重症肝病小组。

    Figure  2.  Recommendations from scholars and societies around the world to unify the definition of ACLF

    图  3  ACLF临床表现分型示意图(‍‍Ⅰ型和Ⅱ型)

    Figure  3.  Schematic diagram of ACLF clinical manifestation classification (Type Ⅰ and Type Ⅱ)

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  • 收稿日期:  2024-10-01
  • 录用日期:  2024-10-20
  • 出版日期:  2024-11-25
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