Abstract: Hyperthyroidism combined with abnormal liver function is a tricky problem in clinical diagnosis and treatment， which mainly includes hyperthyroidism⁃related liver injury， liver injury caused by antithyroid drugs （ATD）， and other liver diseases associated with hyperthyroidism. Chinese Pharmacological Society Professional Committee of Drug⁃induced Diseases， Section of Clinical Toxicology of Chinese Society of Toxicology， and the Editorial Committee of Adverse Drug Reactions Journal organized relevant experts majoring in endocrinology， hepatology， and clinical pharmacy to jointly discuss and formulate this consensus based on a systematic review of relevant research progress at home and abroad， combined with the actual clinical situation in China. This consensus systematically expounds the epidemiology， pathogenesis， clinical characteristics， diagnosis and differential diagnosis， monitoring and treatment of hyperthyroidism with liver dysfunction， and puts forward recommendations for diagnosis and treatment， aiming to help clinicians make reasonable decisions in the prevention， diagnosis and treatment of hyperthyroidism combined with abnormal liver function， and improve the level of clinical diagnosis and treatment.