单纯腹腔镜胆囊切除术与胆囊癌根治术治疗T1b期意外胆囊癌患者的预后比较

刘文龙; 梁斌; 田远虎; 孟翔飞; 余强; 陈继业; 潘颖威; 刘博

doi:10.3969/j.issn.1001-5256.2016.04.031

单纯腹腔镜胆囊切除术与胆囊癌根治术治疗T1b期意外胆囊癌患者的预后比较

DOI: 10.3969/j.issn.1001-5256.2016.04.031

1. 中国人民解放军总医院
2. 北京大学国际医院

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中图分类号: R735.8
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出版历程
- 出版日期: 2016-04-20

A prognostic analysis of laparoscopic versus radical cholecystectomy for T1b unsuspected gallbladder carcinoma

Chinese PLA General Hospital

摘要

摘要:
目的探讨T1b期意外胆囊癌的外科治疗方式及预后情况。方法收集2003年1月-2014年7月中国人民解放军总医院收治的22例T1b期意外胆囊癌患者的临床病理、影像学检查、实验室检查、手术信息以及术后随访资料,比较行胆囊癌根治术与单纯行腹腔镜胆囊切除术患者的术后生存率及复发转移情况。Kaplan-Meier法计算生存率,log-rank法进行生存率检验,计数资料组间比较采用Fisher确切概率法。结果 T1b期意外胆囊癌患者整体1、3、5年累积生存率分别为100%、89.7%和82.8%;单纯行腹腔镜胆囊切除术患者和行根治术患者的5年生存率分别为84.6%和75.0%,差异无统计学意义（χ2=0.000,P=0.991）;单纯行腹腔镜胆囊切除术患者肿瘤转移复发率为15.4%（2/13）,行根治术患者复发率为12.5%（1/8）,2组比较差异无统计学意义（P>0.05）。结论 T1b期意外胆囊癌行胆囊癌根治术是合适的选择。
- 胆囊肿瘤 /
- 胆囊切除术 /
- 预后
Abstract:
Objective To investigate the surgical treatment and prognosis of T1 b unsuspected gallbladder carcinoma( UGC). Methods Twenty- two patients with T1 b UGC admitted to our hospital were enrolled as subjects. The information on clinical pathology,radiological examination,laboratory tests,surgical treatment,and postoperative follow- up were analyzed in patients. The survival rate and recurrence were compared between patients treated with radical cholecystectomy and laparoscopic cholecystectomy. The Kaplan- Meier method was used to calculate survival rates,and the log- rank test was used for survival difference analysis. Comparison of categorical data was made by Fisher's exact test. Results The 1-,3-,and 5- year accumulative survival rates in all patients with T1 b UGC were 100%,89. 7%,and82. 8%,respectively; there was no significant difference in the 5- year accumulative survival rate between patients treated with laparoscopic cholecystectomy and radical cholecystectomy( 84. 6% vs 75. 0%,χ~2= 0. 000,P = 0. 991); two( 15. 4%) out of thirteen patients treated with laparoscopic cholecystectomy respectively; one( 12. 5%) out of eight patients treated with radical cholecystectomy had recurrence,there was no significant difference between the two groups( P > 0. 05). Conclusion Radical cholecystectomy is a superior therapy for T1 b UGC over laparoscopic cholecystectomy.
- gallbladder neoplasms /
- cholecystectomy /
- prognosis

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参考文献(19)

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