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药物性肝损伤的研究进展及我国存在的问题

陈成伟

引用本文:
Citation:

药物性肝损伤的研究进展及我国存在的问题

DOI: 10.3969/j.issn.1001-5256.2018.06.001
详细信息
  • 中图分类号: R575

Research advances in drug-induced liver injury and existing problems in China

  • 摘要: 目前,药物性肝损伤(DILI)已成为临床最常见急性肝损伤的原因。从DILI的发病机制、新的生物标志物、肝脏对药物毒性的耐受、适应与易感性、ALT诊断阈值等方面进行了阐述,提醒应了解诊断量表发展史,以统一标准和认识,要重视草药和膳食补充剂引起的DILI,并深入研究其导致DILI的发病机制,从而预防或减少DILI的发生。我国DILI研究存在的问题和差距是明显的,基础研究相当匮乏,在临床方面也有很多空白,因此,我们要努力跟上国际研究的步伐,使药物更好地为人类服务。

     

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  • 收稿日期:  2018-03-31
  • 出版日期:  2018-06-20
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