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加强基于大数据的药物性肝损伤的科学研究和监管

茅益民

引用本文:
Citation:

加强基于大数据的药物性肝损伤的科学研究和监管

DOI: 10.3969/j.issn.1001-5256.2018.06.005
基金项目: 

“十三五”科技重大专项(2017ZX09304016); 国家自然科学基金课题(81670524); 

详细信息
  • 中图分类号: R575

Strengthening the scientific research and supervision of drug-induced liver injury based on big data

Research funding: 

 

  • 摘要: 药物性肝损伤(DILI)是重要的药源性疾病之一,其临床表型复杂,往往具有不可预测性。由于涉及的药物种类繁多,尤其是复杂的人群异质性,决定了针对DILI的科学研究和监管具有极大的挑战性。目前对于DILI的认知,多来源于国际上长期随访的数据库。然而,DILI领域仍有大量未被满足的临床需求。加强基于大数据DILI的科学研究是更好认知DILI的有效措施,也是科学监管的前提。

     

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出版历程
  • 收稿日期:  2018-03-31
  • 出版日期:  2018-06-20
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