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土三七致急性肝小静脉闭塞症1例报告

屈伟鸽 蔡艳俊 孙晓峰 齐月

引用本文:
Citation:

土三七致急性肝小静脉闭塞症1例报告

DOI: 10.3969/j.issn.1001-5256.2019.02.029
基金项目: 

国家自然科学基金项目(81600468); 

详细信息
  • 中图分类号: R285.6

A case of acute hepatic venular occlusive disease caused by Gynura segetum

Research funding: 

 

  • 摘要: <正>肝小静脉闭塞症(hepatic venular occlusion disease,HVOD)又称肝窦阻塞综合征,其病理过程是肝小叶中央静脉和内皮下静脉内皮细胞受损、肿胀、纤维化,引起血管狭窄和闭塞,从而导致肝细胞萎缩,肝脏弥漫性纤维化等。我国HVOD常见病因主要是接触吡啶类生物碱(pyridine alkaloids,PA),如土三七、千里光等,而西方国家因造血干细胞移植相关的化疗药物、免疫抑制剂的应用所致HVOD较常见[1-3]。研究[3]表明,90%患者

     

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