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辛伐他汀治疗肝硬化门静脉高压症的作用机制及应用现状

吴欢 伍龙 杨京

引用本文:
Citation:

辛伐他汀治疗肝硬化门静脉高压症的作用机制及应用现状

DOI: 10.3969/j.issn.1001-5256.2019.02.037
详细信息
  • 中图分类号: R575.21

Mechanism and current status of simvastatin in treatment of cirrhotic portal hypertension

  • 摘要: 门静脉高压症被认为是继病因之后推动肝功能减退的重要生理环节。通过对相关文献的归纳总结得出,与传统防治门静脉高压症药物相比,辛伐他汀可通过诱导Kruppel样因子2及一氧化氮的表达,达到改善肝功能及降低肝硬化门静脉压力的作用,分析表明辛伐他汀在改善肝硬化门静脉血流动力学方面有广泛应用前景。

     

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  • 收稿日期:  2018-09-17
  • 出版日期:  2019-02-20
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