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酒精性胰腺炎的流行病学特征、发病机制及诊疗进展

胡江峰 陆伦根

引用本文:
Citation:

酒精性胰腺炎的流行病学特征、发病机制及诊疗进展

DOI: 10.3969/j.issn.1001-5256.2019.02.047
详细信息
  • 中图分类号: R576;R181.3

Research advances in the epidemiological features, pathogenesis, and diagnosis and treatment of alcoholic pancreatitis

  • 摘要: 酒精性胰腺炎发病量较十年前明显增多,其发病涉及基因、吸烟、肠道菌群等多方面因素,在流行病学特点、临床表现等方面与其他类型胰腺炎均有所不同。综述了近年酒精性胰腺炎的流行病学特征、发病机制、临床表现、治疗和预后方面的研究进展。

     

  • [1]ZHU Y, PAN X, ZENG H.A study on the etiology, severity, and mortality of 3260 patients with acute pancreatitis according to the revised Atlanta classification in Jiangxi, China over an 8-year period[J].Pancreas, 2017, 46 (4) :504-509.
    [2]WANG GJ, GAO CF, WEI D, et al.Acute pancreatitis:Etiology and common pathogenesis[J].World J Gastroenterol, 2009, 15 (12) :1427-1430.
    [3]LU ZY, ZHONG NS.Internal medicine[M].7th Edition.Beijing:People's Medical Publishing House, 2008:379-380. (in Chinese) 陆再英, 钟南山.内科学[M].7版.北京:人民卫生出版社, 2008:379-380.
    [4]WANG JY, LIAO EY, HUANG CX.Internal medicine (8-year medical program) [M].2th Edition.Beijing:People's Medical Publishing House, 2010:555-556. (in Chinese) 王吉耀, 廖二元, 黄从新.内科学 (八年制) [M].2版.北京:人民卫生出版社, 2010:555-556.
    [5]BHARDWAJ P, GARG PK, MAULIK SK.A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis[J].Gastroenterology, 2009, 136 (1) :149-159.e2.
    [6]KARJULA H, SAARELA A, OHTONEN P.Long-term outcome and causes of death for working-age patients hospitalized due to acute pancreatitis with a median follow-up of 10years[J].Ann Surg, 2017.[Epub ahead of print]
    [7]CONWELL DL, BANKS PA, SANDHU BS.Validation of demographics, etiology, and risk factors for chronic pancreatitis in the USA:A report of the North American Pancreas Study (NAPS) Group[J].Dig Dis Sci, 2017, 62 (8) :2133-2140.
    [8]ZHENG Y, ZHOU Z, LI H.A multicenter study on etiology of acute pancreatitis in Beijing during 5 years[J].Pancreas, 2015, 44 (3) :409-414.
    [9]KUME K, MASAMUNE A, ARIGA H, et al.Alcohol consumption and the risk for developing pancreatitis:A case-control study in Japan[J].Pancreas, 2015, 44 (1) :53-58.
    [10]SAMOKHVALOV AV, REHM J, ROERECKE M.Alcohol consumption as a risk factor for acute and chronic pancreatitis:Asystematic review and a series of Meta-analyses[J].EBioMedicine, 2015, 2 (12) :1996-2002.
    [11]LANKISCH PG, APTE M, BANKS PA, et al.Acute pancreatitis[J].Lancet, 2015, 386 (9988) :85-96.
    [12]CLEMENS DL, SCHNEIDER KJ, ARKFELD CK.Alcoholic pancreatitis:New insights into the pathogenesis and treatment[J].World J Gastrointest Pathophysiol, 2016, 7 (1) :48-58.
    [13]WHITCOMB DC, LARUSCH J, KRASINSKAS AM.Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis[J].Nat Genet, 2012, 44 (12) :1349-1354.
    [14]DERIKX MH, KOVACS P, SCHOLZ M.Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study[J].Gut, 2015, 64 (9) :1426-1433.
    [15]ROSENDAHL J, KIRSTEN H, HEGYI E.Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis[J].Gut, 2017, 67 (10) :1855-1863.
    [16]MAISONNEUVE P, LOWENFELS AB, MULLHAUPT B.Cigarette smoking accelerates progression of alcoholic chronic pancreatitis[J].Gut, 2005, 54 (4) :510-514.
    [17]LUGEA A, GERLOFF A, SU HY.The Combination of alcohol and cigarette smoke induces endoplasmic reticulum stress and cell death in pancreatic acinar cells[J].Gastroenterology, 2017, 153 (6) :1674-1686.
    [18]CIOCAN D, REBOURS V, VOICAN CS.Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis[J].Sci Rep, 2018, 8 (1) :4822.
    [19]CUI ML, KIM KH, KIM HG.Incidence, risk factors and clinical course of pancreatic fluid collections in acute pancreatitis[J].Dig Dis Sci, 2014, 59 (5) :1055-1062.
    [20]HOLLEMANS RA, HALLENSLEBEN NDL, MAGER DJ.Pancreatic exocrine insufficiency following acute pancreatitis:Systematic review and study level meta-analysis[J].Pancreatology, 2018, 18 (3) :253-262.
    [21]YANG L, XU J, LAI XR, et al.Effect of nutritional support on the prognosis of patients with acute pancreatitis[J].Chin JMed Offic, 2018, 46 (7) :790-793. (in Chinese) 杨蕾, 徐静, 赖晓蕊, 等.不同营养支持方式对急性胰腺炎预后影响[J].临床军医杂志, 2018, 46 (7) :790-793.
    [22]NIKKOLA J, RATY S, LAUKKARINEN J, et al.Abstinence after first acute alcohol-associated pancreatitis protects against recurrent pancreatitis and minimizes the risk of pancreatic dysfunction[J].Alcohol Alcohol, 2013, 48 (4) :483-486.
    [23]SHI XM, WEI SC.Analysis of clinical efficacy of compound azintamide enteric-coated tablets in the treatment of chronic alcoholic pancreatitis indigestion[J].Syst Med, 2017, 20 (2) :48-50, 53. (in Chinese) 史晓盟, 魏思忱.泌特治疗慢性酒精性胰腺炎消化不良临床疗效分析[J].系统医学, 2017, 20 (2) :48-50, 53.
    [24]AHMED ALI U, ISSA Y, HAGENAARS JC.Risk of recurrent pancreatitis and progression to chronic pancreatitis after a first episode of acute pancreatitis[J].Clin Gastroenterol Hepatol, 2016, 14 (5) :738-746.
    [25]CHO JH, KIM TN, KIM SB.Comparison of clinical course and outcome of acute pancreatitis according to the two main etiologies:Alcohol and gallstone[J].BMC Gastroenterol, 2015, 15 (1) :87.
    [26]HAO L, WANG LS, LIU Y.The different course of alcoholic and idiopathic chronic pancreatitis:A long-term study of2037 patients[J].PLo S One, 2018, 13 (6) :e0198365.
    [27]CROCKETT SD, WANI S, GARDNER TB.American Gastroenterological Association Institute Guideline on initial management of acute pancreatitis[J].Gastroenterology, 2018, 154 (4) :1096-1101.
    [28]GBD 2016 Alcohol Collaborators.Alcohol use and burden for195 countries and territories, 1990-2016:A systematic analysis for the Global Burden of Disease Study 2016[J].The Lancet, 2018, 392 (10152) :1015-1035.
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  • 收稿日期:  2018-09-05
  • 出版日期:  2019-02-20
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