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STAT3:慢性炎症介导肝癌进程的关键分子

音金萍 岳紫晨 卓少元

引用本文:
Citation:

STAT3:慢性炎症介导肝癌进程的关键分子

DOI: 10.3969/j.issn.1001-5256.2020.04.054
基金项目: 

国家自然科学基金地区科学基金项目(81660775,81860824); 

详细信息
  • 中图分类号: R735.7

STAT3: A key molecule in the progression of liver cancer mediated by chronic inflammation

Research funding: 

 

  • 摘要: STAT3是信号转导及转录激活因子家族成员,在肝癌等慢性炎症相关性肿瘤中异常激活。作为肝癌炎症微环境中的关键信号分子,STAT3不仅参与肝癌发生过程中的"炎癌转化",而且通过多种方式促进肝癌进展中癌细胞的增殖、侵袭与转移,是一个潜在的肝癌治疗靶标。综述了近几年STAT3与肝癌关系的新进展。

     

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  • 出版日期:  2020-04-20
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