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肝纤维化逆转的研究进展

李满彪 李金玉 冯对平

引用本文:
Citation:

肝纤维化逆转的研究进展

DOI: 10.3969/j.issn.1001-5256.2023.01.030
基金项目: 

山西省重点研发计划社会发展项目 (201903D321188)

山西省科学技术厅面上项目 (20210302123258)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:李满彪负责拟定写作思路,检索文献,撰写论文;冯对平、李金玉负责指导、修改论文并最终定稿。
详细信息
    通信作者:

    冯对平, fengdp@sxmu.edu.cn (ORCID: 0000-0003-4516-3797)

Research advances in the reversal of liver fibrosis

Research funding: 

Social Development Project of Shanxi Key Research and Development Plan (201903D321188);

Department of Science and Technology of Shanxi Province, General Project (20210302123258)

More Information
  • 摘要: 任何病因引起的慢性肝损伤都会导致肝纤维化,过去认为肝纤维化是一种静态的、不可逆转的病理生理过程。近年来,随着分子生物学的飞速发展,以及对肝脏微观层面的不断深入研究,越来越多的证据表明肝纤维化是一种动态的、可逆的过程。本文回顾了不同方法评价各种病因导致的肝纤维化逆转的报道,总结了肝纤维化的发病机制及其逆转的机制,并回顾了逆转的治疗药物,归纳目前肝纤维化的评估方法,最后认为及时清除或控制潜在病因,肝纤维化会出现不同程度的逆转。

     

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  • 收稿日期:  2022-05-15
  • 录用日期:  2022-07-14
  • 出版日期:  2023-01-20
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