In April 2025, Global consensus recommendations for metabolic dysfunction-associated steatotic liver disease and steatohepatitis was published online in
Gastroenterology. These recommendations address the areas with significant divergence, such as metabolic dysfunction-associated steatotic liver disease (MASLD) screening steps, the use of noninvasive tests for risk stratification, management of comorbidities, and the recent advances in resmetirom for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), covering the most debated topics in current MASLD management. This article makes an excerpt of the main contents in these consensus recommendations.