ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 3
Mar.  2023
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Article Contents

Role of serum Golgi protein 73 in nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2023.03.028
Research funding:

Shanxi Province Science and Technology Achievement Transformation Guidance Special Project (201904D131030)

More Information
  • Corresponding author: LIU Jinchun, zxr610624@163.com (ORCID: 0000-0002-1984-6802)
  • Received Date: 2022-07-06
  • Accepted Date: 2022-08-21
  • Published Date: 2023-03-20
  • Golgi protein 73 (GP73) is a Golgi transmembrane protein that can be released into blood by cleavage. An increasing number of studies have shown that the increase in serum GP73 is closely associated with the development and progression of nonalcoholic fatty liver disease (NAFLD) and serum GP73 is expected to be used as a potential serological marker for the diagnosis and assessment of NAFLD. This article reviews the research advances in serum GP73 in NAFLD and analyzes its potential mechanism of action, so as to provide new options for the therapeutic targets of NAFLD.


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