中文｜English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 11
Nov.  2023
Turn off MathJax
Article Contents
Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(11): 2538-2542

Research advances in the interspecies transmission of hepatitis E virus

DOI: 10.3969/j.issn.1001-5256.2023.11.004

  • Medical Faculty of Kunming University of Science and Technology，Kunming 650500，China

Research funding:

‍National Natural Science Foundation of China (82260396);

Natural Science Foundation for Distinguished Young Scholars of Yunnan Province (202001AV070005);

Program for Innovative Research Team （in Science and Technology） in University of Yunnan Province (2020)

More Information
  • Corresponding author: HUANG Fen， huangfen6789@163.com （ORCID： 0000-0001-9147-2537）
  • Received Date: 2023-04-23
  • Accepted Date: 2023-05-26
  • Published Date: 2023-11-28
    Abstract
  • Hepatitis E virus （HEV） is a pathogen for viral hepatitis and can be transmitted across species via animals. The incidence rate of hepatitis E caused by HEV infection ranks first among acute viral hepatitis worldwide， and now it has become a major public health issue that threatens human health. In recent years， more and more species have been identified as the natural hosts of HEV， and there are more routes for the interspecies transmission of HEV， which greatly inhibits the prevention and control of this virus. Therefore， this article reviews and discusses the advances in the interspecies transmission of HEV， so as to provide a reference for the prevention and control of HEV.

     

    • FullText(HTML)
  • loading
    • References(47)
  • [1]
    SAYED IM, VERCOUTER AS, ABDELWAHAB SF, et al. Is hepatitis E virus an emerging problem in industrialized countries?[J]. Hepatology, 2015, 62( 6): 1883- 1892. DOI: 10.1002/hep.27990.
    [2]
    Chinese Society of Hepatology, Chinese Medical Association. Consensus on prevention and treatment of hepatitis E[J]. Chin J Hepatol, 30( 8): 820- 831. DOI: 10.3760/cma.j.cn501113-20220729-00401.

    中华医学会肝病学分会. 戊型肝炎防治共识[J]. 中华肝脏病杂志, 30( 8): 820- 831. DOI: 10.3760/cma.j.cn501113-20220729-00401.
    [3]
    LI PF, LIU JY, LI Y, et al. The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis[J]. Liver Int, 2020, 40( 7): 1516- 1528. DOI: 10.1111/liv.14468.
    [4]
    PATRA S, KUMAR A, TRIVEDI SS, et al. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection[J]. Ann Intern Med, 2007, 147( 1): 28. DOI: 10.7326/0003-4819-147-1-200707030-00005.
    [5]
    KAMAR N, GARROUSTE C, HAAGSMA EB, et al. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants[J]. Gastroenterology, 2011, 140( 5): 1481- 1489. DOI: 10.1053/j.gastro.2011.02.050.
    [6]
    Chinese Consortium for the Study of Hepatitis E(CCSHE), Chinese Physician Association for Infectious Disease, National Clinical Research Center for Infectious Diseases. Expert consensus on the process of in-hospital screening and management of viral hepatitis E in China(2023)[J]. J Clin Hepatol, 2023, 39( 4): 785- 794. DOI: 10.3969/j.issn.1001-5256.2023.04.008.

    中国戊型肝炎研究协助组(CCSHE), 中国医师协会感染科医师分会, 国家感染性疾病临床医学研究中心. 中国戊型病毒性肝炎院内筛查管理流程专家共识(2023年版)[J]. 临床肝胆病杂志, 2023, 39( 4): 785- 794. DOI: 10.3969/j.issn.1001-5256.2023.04.008.
    [7]
    European Association for The Study of The Liver. EASL Clinical Practice Guidelines on hepatitis E virus infection[J]. J Hepatol, 2018, 68( 6): 1256- 1271. DOI: 10.1016/j.jhep.2018.03.005.
    [8]
    NIMGAONKAR I, DING Q, SCHWARTZ RE, et al. Hepatitis E virus: Advances and challenges[J]. Nat Rev Gastroenterol Hepatol, 2018, 15( 2): 96- 110. DOI: 10.1038/nrgastro.2017.150.
    [9]
    MENG XJ, PURCELL RH, HALBUR PG, et al. A novel virus in swine is closely related to the human hepatitis E virus[J]. Proc Natl Acad Sci USA, 1997, 94( 18): 9860- 9865. DOI: 10.1073/pnas.94.18.9860.
    [10]
    PAVIO N, DOCEUL V, BAGDASSARIAN E, et al. Recent knowledge on hepatitis E virus in Suidae Reservoirs and transmission routes to human[J]. Vet Res, 2017, 48( 1): 78. DOI: 10.1186/s13567-017-0483-9.
    [11]
    TAKAHASHI H, TANAKA T, JIRINTAI S, et al. A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus(HEV) strains: Demonstration of HEV infectivity of porcine liver sold as food[J]. Arch Virol, 2012, 157( 2): 235- 246. DOI: 10.1007/s00705-011-1153-2.
    [12]
    WIDÉN F, SUNDQVIST L, MATYI-TOTH A, et al. Molecular epidemiology of hepatitis E virus in humans, pigs and wild boars in Sweden[J]. Epidemiol Infect, 2011, 139( 3): 361- 371. DOI: 10.1017/S0950268810001342.
    [13]
    ROSE N, LUNAZZI A, DORENLOR V, et al. High prevalence of Hepatitis E virus in French domestic pigs[J]. Comp Immunol Microbiol Infect Dis, 2011, 34( 5): 419- 427. DOI: 10.1016/j.cimid.2011.07.003.
    [14]
    PAVIO N, MERBAH T, THÉBAULT A. Frequent hepatitis E virus contamination in food containing raw pork liver, France[J]. Emerg Infect Dis, 2014, 20( 11): 1925- 1927. DOI: 10.3201/eid2011.140891.
    [15]
    BOUWKNEGT M, LODDER-VERSCHOOR F, VAN DER POEL WHM, et al. Hepatitis E virus RNA in commercial porcine livers in The Netherlands[J]. J Food Prot, 2007, 70( 12): 2889- 2895. DOI: 10.4315/0362-028x-70.12.2889.
    [16]
    SATO Y, SATO H, NAKA K, et al. A nationwide survey of hepatitis E virus(HEV) infection in wild boars in Japan: Identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes[J]. Arch Virol, 2011, 156( 8): 1345- 1358. DOI: 10.1007/s00705-011-0988-x.
    [17]
    TEI S, KITAJIMA N, TAKAHASHI K, et al. Zoonotic transmission of hepatitis E virus from Deer to human beings[J]. Lancet, 2003, 362( 9381): 371- 373. DOI: 10.1016/S0140-6736(03)14025-1.
    [18]
    ANHEYER-BEHMENBURG HE, SZABO K, SCHOTTE U, et al. Hepatitis E virus in wild boars and spillover infection in red and roe Deer, Germany, 2013-2015[J]. Emerg Infect Dis, 2017, 23( 1): 130- 133. DOI: 10.3201/eid2301.161169.
    [19]
    GO HJ, PARK BJ, AHN HS, et al. Identification of hepatitis E virus in bovine and porcine raw livers[J]. J Microbiol Biotechnol, 2019, 29( 12): 2022- 2025. DOI: 10.4014/jmb.1910.10059.
    [20]
    LI S, LIU MX, CONG JJ, et al. Detection and characterization of hepatitis E virus in goats at slaughterhouse in Tai’an region, China[J]. Biomed Res Int, 2017, 2017: 3723650. DOI: 10.1155/2017/3723650.
    [21]
    WU JY, SI FS, JIANG CY, et al. Molecular detection of hepatitis E virus in sheep from southern Xinjiang, China[J]. Virus Genes, 2015, 50( 3): 410- 417. DOI: 10.1007/s11262-015-1194-9.
    [22]
    HUANG F, LI YL, YU WH, et al. Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis[J]. Hepatology, 2016, 64( 2): 350- 359. DOI: 10.1002/hep.28668.
    [23]
    TREAGUS S, WRIGHT C, BAKER-AUSTIN C, et al. The foodborne transmission of hepatitis E virus to humans[J]. Food Environ Virol, 2021, 13( 2): 127- 145. DOI: 10.1007/s12560-021-09461-5.
    [24]
    LI TC, ZHOU XF, YOSHIZAKI S, et al. Production of infectious dromedary camel hepatitis E virus by a reverse genetic system: Potential for zoonotic infection[J]. J Hepatol, 2016, 65( 6): 1104- 1111. DOI: 10.1016/j.jhep.2016.07.013.
    [25]
    WANG L, TENG JLL, LAU SKP, et al. Transmission of a novel genotype of hepatitis E virus from Bactrian camels to Cynomolgus macaques[J]. J Virol, 2019, 93( 7): e02014- e02018. DOI: 10.1128/JVI.02014-18.
    [26]
    DEMIRCI M, YIĞIN A, ÜNLÜ Ö, et al. Detection of HEV RNA amounts and genotypes in raw milks obtained from different animals[J]. Mikrobiyol Bul, 2019, 53( 1): 43- 52. DOI: 10.5578/mb.67468.
    [27]
    EL-MOKHTAR MA, ELKHAWAGA AA, SAYED IM. Assessment of hepatitis E virus(HEV) in the edible goat products pointed out a risk for human infection in Upper Egypt[J]. Int J Food Microbiol, 2020, 330: 108784. DOI: 10.1016/j.ijfoodmicro.2020.108784.
    [28]
    MESQUITA JR, SANTOS-FERREIRA N, FERREIRA AS, et al. Increased risk of hepatitis E virus infection in workers occupationally exposed to sheep[J]. Transbound Emerg Dis, 2020. DOI: 10.1111/tbed.13524.
    [29]
    SAYED IM, ELKHAWAGA AA, EL-MOKHTAR MA. Circulation of hepatitis E virus(HEV) and/or HEV-like agent in non-mixed dairy farms could represent a potential source of infection for Egyptian people[J]. Int J Food Microbiol, 2020, 317: 108479. DOI: 10.1016/j.ijfoodmicro.2019.108479.
    [30]
    PURCELL RH, ENGLE RE, ROOD MP, et al. Hepatitis E virus in rats, los angeles, California, USA[J]. Emerg Infect Dis, 2011, 17( 12): 2216- 2222. DOI: 10.3201/eid1712.110482.
    [31]
    World Health Organization. Global hepatitis report, 2017[OR/OL]. http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/. http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/
    [32]
    REUTER G, BOROS Á, PANKOVICS P. Review of hepatitis E virus in rats: Evident risk of species Orthohepevirus C to human zoonotic infection and disease[J]. Viruses, 2020, 12( 10): 1148. DOI: 10.3390/v12101148.
    [33]
    WANG B, HARMS D, YANG XL, et al. Orthohepevirus C: An expanding species of emerging hepatitis E virus variants[J]. Pathogens, 2020, 9( 3): 154. DOI: 10.3390/pathogens9030154.
    [34]
    ABRAVANEL F, LHOMME S, COSTA H EL, et al. Rabbit hepatitis E virus infections in humans, France[J]. Emerg Infect Dis, 2017, 23( 7): 1191- 1193. DOI: 10.3201/eid2307.170318.
    [35]
    PRIMADHARSINI PP, NAGASHIMA S, OKAMOTO H. Mechanism of cross-species transmission, adaptive evolution and pathogenesis of hepatitis E virus[J]. Viruses, 2021, 13( 5): 909. DOI: 10.3390/v13050909.
    [36]
    LIANG HB, CHEN JD, XIE JX, et al. Hepatitis E virus serosurvey among pet dogs and cats in several developed cities in China[J]. PLoS One, 2014, 9( 6): e98068. DOI: 10.1371/journal.pone.0098068.
    [37]
    LI YL, QU CB, SPEE B, et al. Hepatitis E virus seroprevalence in pets in the Netherlands and the permissiveness of canine liver cells to the infection[J]. Ir Vet J, 2020, 73: 6. DOI: 10.1186/s13620-020-00158-y.
    [38]
    ZENG MY, GAO H, YAN XX, et al. High hepatitis E virus antibody positive rates in dogs and humans exposed to dogs in the south-west of China[J]. Zoonoses Public Health, 2017, 64( 8): 684- 688. DOI: 10.1111/zph.12377.
    [39]
    SONG YJ, JEONG HJ, KIM YJ, et al. Analysis of complete genome sequences of swine hepatitis E virus and possible risk factors for transmission of HEV to humans in Korea[J]. J Med Virol, 2010, 82( 4): 583- 591. DOI: 10.1002/jmv.21730.
    [40]
    RIVADULLA E, VARELA MF, MESQUITA JR, et al. Detection of hepatitis E virus in shellfish harvesting areas from Galicia(northwestern Spain)[J]. Viruses, 2019, 11( 7): 618. DOI: 10.3390/v11070618.
    [41]
    WARREN CJ, SAWYER SL. How host genetics dictates successful viral zoonosis[J]. PLoS Biol, 2019, 17( 4): e3000217. DOI: 10.1371/journal.pbio.3000217.
    [42]
    SHUKLA P, NGUYEN HT, TORIAN U, et al. Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant[J]. Proc Natl Acad Sci USA, 2011, 108( 6): 2438- 2443. DOI: 10.1073/pnas.1018878108.
    [43]
    DALTON HR, BENDALL RP, KEANE FE, et al. Persistent carriage of hepatitis E virus in patients with HIV infection[J]. N Engl J Med, 2009, 361( 10): 1025- 1027. DOI: 10.1056/NEJMc0903778.
    [44]
    FEAGINS AR, CÓRDOBA L, SANFORD BJ, et al. Intergenotypic chimeric hepatitis E viruses(HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs[J]. Virus Res, 2011, 156( 1-2): 141- 146. DOI: 10.1016/j.virusres.2010.12.011.
    [45]
    BOUQUET J, CHEREL P, PAVIO N. Genetic characterization and codon usage bias of full-length Hepatitis E virus sequences shed new lights on genotypic distribution, host restriction and genome evolution[J]. Infect Genet Evol, 2012, 12( 8): 1842- 1853. DOI: 10.1016/j.meegid.2012.07.021.
    [46]
    ZHOU JH, LI XR, LAN X, et al. The genetic divergences of codon usage shed new lights on transmission of hepatitis E virus from swine to human[J]. Infect Genet Evol, 2019, 68: 23- 29. DOI: 10.1016/j.meegid.2018.11.024.
    [47]
    BAHA S, BEHLOUL N, LIU ZZ, et al. Comprehensive analysis of genetic and evolutionary features of the hepatitis E virus[J]. BMC Genomics, 2019, 20( 1): 790. DOI: 10.1186/s12864-019-6100-8.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (247) PDF downloads(51) Cited by()
    Proportional views
    Related
        

    The first journal specializing in hepatobiliary and pancreatic diseases in China

    Supervisor：Ministry of Education of the People's Republic of China

    Sponsor：Jilin University

    Academic Support: Chinese Society of Hepatology，Chinese Medical Association

    Address: 461 Xinjiang Road, Changchun

    Submit：0431-88782044

    Peer review：0431-88783542

    Email：lcgdb@vip.163.com

    About Journal

    Submission Guideline

    Journal Online

    Hepatobiliary College

    Guidelines

    YesterdayIP[]YesterdayPV[]TodayIP[]TodayPV[]Online[]

    Website Design © 2020 Editorial Board of Journal of Clinical Hepatology 吉ICP备10000617号-1 Supported by: Beijing Renhe Information Technology Co. Ltd  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return