中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

2011版《NCCN胰腺癌临床实践指南》中若干问题的探讨

刘子文 赵玉沛

引用本文:
Citation:

2011版《NCCN胰腺癌临床实践指南》中若干问题的探讨

详细信息
  • 中图分类号: R735.9

The discussion on the issues related to NCCN clinical practice guidelines in oncology for pancreatic adenocarcinoma (V2011)

  • 摘要: 《NCCN胰腺癌临床实践指南》2011中国版已修订完成,新版指南在原有内容基础上结合近年来临床研究进展,在胰腺癌的诊断和治疗路线、原则、循证医学证据上进行了细微更新,并在理念上有了新的阐述,本文就更新中的相关问题进行探讨。《NCCN胰腺癌临床实践指南》2011版中针对胰腺癌的诊断提出了多学科评估的理念,治疗上重视肿瘤可切除性判定标准,化疗中对于体力状态好的患者可选用FOLFIRINOX方案,强调了吉西他滨和5-氟尿嘧啶(5-FU)均作为胰腺癌化疗的I类证据。

     

  • [1]Callery MP, Chang KJ, Fishman EK, et al.Pretreatment as-sessment of resectable and borderline resectable pancreaticcancer:expert consensus statement[J].Ann Surg Oncol, 2009, 16 (7) :1727-1733.
    [2]Klauss M, Schobinger M, Wolf I, et al.Value of three-di-mensional reconstructions in pancreatic carcinoma using mul-tidetector CT:initial results[J].World J Gastroenterol, 2009, 15 (46) :5827-5832.
    [3]McNulty NJ, Francis IR, Platt JF, et al.Multi——detectorrow helical CT of the pancreas:effect of contrast-enhancedmultiphasic imaging on enhancement of the pancreas, peripancreatic vasculature, and pancreatic adenocarcinoma[J].Radiology, 2001, 220 (1) :97-102.
    [4]Farma JM, Santillan AA, Melis M, et al.PET/CT fusion scanenhances CT staging in patients with pancreatic neoplasms[J].Ann Surg Oncol, 2008, 15 (9) :2465-2471.
    [5]Varadarajulu S, Wallace MB.Applications of endoscopic ul-trasonography in pancreatic cancer[J].Cancer Control, 2004, 11 (1) :15-22.
    [6]Ahmed SI, Bochkarev V, Oleynikov D, et al.Sasson AR.Patients with pancreatic adenocarcinoma benefit from staginglaparoscopy[J].J Laparoendosc Adv Surg Tech A, 2006, 16 (5) :458-463.
    [7]Birkmeyer JD, Siewers AE, Finlayson EV, et al.Hospital vol-ume and surgical mortality in the United States[J].N Engl JMed, 2002, 346 (15) :1128-1137.
    [8]Bilimoria KY, Bentrem DJ, Ko CY, et al.Multimodality thera-py for pancreatic cancer in the U.S.:utilization, outcomes, and the effect of hospital volume[J].Cancer, 2007, 110 (6) :1227-1234.
    [9]Neoptolemos JP, Stocken DD, Bassi C, et al.Adjuvant chemo-therapy with fluorouracil plus folinic acid vs gemcitabine follow-ing pancreatic cancer resection:a randomized controlled trial[J].JAMA, 2010, 304 (10) :1073-1081.
    [10]Van Laethem JL, Hammel P, Mornex F, et al.Adjuvantgemcitabine alone versus gemcitabine-based chemoradio-therapy after curative resection for pancreatic cancer:a ran-domized EORTC-40013-22012/FFCD-9203/GERCORphase II study[J].J Clin Oncol, 2010, 28 (29) :4450-4456.
    [11]Murphy JD, Adusumilli S, Griffith KA, et al.Full-dose gemcit-abine and concurrent radiotherapy for unresectable pancreaticcancer[J].Int J Radiat Oncol Biol Phys, 2007, 68 (3) :801-808.
    [12]Ychou M, Conroy T, Seitz JF, et al.An open phase I studyassessing the feasibility of the triple combination:oxaliplatin plus irinotecan plus leucovorin/5-fluorouracil every 2 weeksin patients with advanced solid tumors[J].Ann Oncol, 2003, 14 (3) :481-489.
    [13]Conroy T, Desseigne F, Ychou M, et al.Randomized phaseIII trial comparing FOLFIRINOX (F:5FU/leucovorin[LV], iri-notecan[I], and oxaliplatin[O]) versus gemcitabine (G) as first-line treatment for metastatic pancreatic adenocarci-noma (MPA) :Preplanned interim analysis results of the PRODIGE 4/ACCORD 11 trial[J].J Clin Oncol, 2010, 28 (15suppl) :4010.
    [14]Finkelberg DL, Sahani D, Deshpande V, et al.Autoimmunepancreatitis[J].N Engl J Med, 2006, 355:2670-2676.
  • 加载中
计量
  • 文章访问数:  3681
  • HTML全文浏览量:  23
  • PDF下载量:  823
  • 被引次数: 0
出版历程
  • 收稿日期:  2011-09-13
  • 出版日期:  2011-11-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回