巨大胆囊腺瘤误诊为胆囊癌1例报告

王悦华; 江华; 滕梁红; 段焕利; 崔壁霄; 王冬梅

doi:10.12449/JCH240424

巨大胆囊腺瘤误诊为胆囊癌1例报告

DOI: 10.12449/JCH240424

a.
首都医科大学宣武医院普外科，北京 100053
b.
首都医科大学宣武医院病理科，北京 100053
c.
首都医科大学宣武医院放射科，北京 100053

基金项目:

教育部人文社会科学研究规划基金项目 (14YJAZH083)

伦理学声明：本例报告已获得患者知情同意。

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：王悦华、江华负责病例诊疗及文章的撰写；滕梁红、段焕利负责病理分析；崔壁霄负责影像资料分析；王冬梅负责病例随诊及文献整理。

详细信息

通信作者:
王悦华， wangyuehua301@sina.com （ORCID： 0000-0003-4707-3912）

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出版历程
- 收稿日期: 2023-06-09
- 录用日期: 2023-08-01
- 出版日期: 2024-04-11

Giant adenoma of the gallbladder misdiagnosed as gallbladder carcinoma： A case report

a.
Department of General Surgery, Xuanwu Hospital，Capital Medical University，Beijing 100053，China
b.
Department of Pathology, Xuanwu Hospital，Capital Medical University，Beijing 100053，China
c.
Department of Radiology，Xuanwu Hospital，Capital Medical University，Beijing 100053，China

Research funding:

Humanities and Social Sciences Planning Fund Project of Ministry of Education (14YJAZH083)

More Information

Corresponding author: WANG Yuehua， wangyuehua301@sina.com （ORCID： 0000-0003-4707-3912）

摘要

摘要: 1例胆囊肿物患者，曾出现一过性黄疸，经腹部超声、增强CT、MRCP及PET-CT检查，均诊断为胆囊癌。手术探查见胆囊增大，胆囊颈部肿物挤压肝门部，但没有肿瘤侵犯表现，肝脏未见肿瘤转移征象，仅为患者行胆囊切除术。病理诊断为胆囊管状腺瘤，未见癌变。本病例特点是胆囊肿瘤巨大，影像未见肿瘤边缘浸润，病理未见恶变。
- 胆囊肿瘤 /
- 腺瘤 /
- 胆囊切除术 /
- 误诊
Abstract: One patient with gallbladder mass had transient jaundice and was diagnosed with gallbladder carcinoma by abdominal ultrasonography， contrast-enhanced CT， MRCP， and PET-CT. Surgical exploration showed enlarged gallbladder and a mass in the neck of the gallbladder pressing against the hilum of the liver， with no manifestation of tumor invasion， and there were no signs of liver metastasis. Only cholecystectomy was performed for the patient. The pathological diagnosis was tubular adenoma of the gallbladder without carcinogenesis. This case is characterized by a large gallbladder tumor， without marginal infiltration on imaging or malignant transformation based on pathology.
- Gallbladder Neoplasms /
- Adenoma /
- Cholecystectomy /
- Diagnostic Errors

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图 1 增强CT检查结果

注： a，胆囊肿瘤压迫肝门部；b，胆囊肿瘤位于胆囊颈部。

Figure 1. Results of enhanced CT scan

下载: 全尺寸图片幻灯片

图 2 MRCP检查结果

注： a，胆囊肿瘤压迫肝门部；b，胆囊肿瘤位于胆囊颈部。

Figure 2. Results of MRCP

下载: 全尺寸图片幻灯片

图 3 PET-CT检查结果

注： a，全身扫描；b，胆囊肿物表现。

Figure 3. Results of PET-CT

下载: 全尺寸图片幻灯片

图 4 胆囊大体表现

注： a，术中所见胆囊；b，切除的胆囊标本及肿物。

Figure 4. General manifestations of the gallbladder

下载: 全尺寸图片幻灯片

图 5 胆囊肿瘤病理形态学表现

注： a，肿物呈息肉样生长，可见细蒂，胆囊壁未明显增厚（HE，×8）；b，肿物呈筛状及乳头状生长，细胞具有异型性（HE，×10）；c，肿物呈筛状及实性生长，伴鳞状上皮化生（HE，×4）；d，局部肿瘤细胞结构复杂，核异型性明显，可见核分裂象，呈高级别异型增生（HE，×20）。

Figure 5. Pathomorphological findings of gallbladder tumors

下载: 全尺寸图片幻灯片

参考文献(11)

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