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他汀类药物在慢性肝病中的作用

杨希坤 李晖 曾子键 吴旋 王凯鑫

引用本文:
Citation:

他汀类药物在慢性肝病中的作用

DOI: 10.12449/JCH241029
基金项目: 

国家自然科学基金面上项目 (82274323)

利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:杨希坤负责撰写论文;曾子键、吴旋、王凯鑫参与查找文献,修改论文;李晖负责拟定写作思路,指导论文撰写并最后定稿。
详细信息
    通信作者:

    李晖, 1400124746@qq.com (ORCID: 0000-0002-5919-1396)

Role of statins in chronic liver disease

Research funding: 

General Project of National Natural Science Foundation of China (82274323)

More Information
    Corresponding author: LI Hui, 1400124746@qq.com (ORCID: 0000-0002-5919-1396)
  • 摘要: 慢性肝病是肝脏由炎症、纤维化,向肝硬化、肝癌进展的“魔鬼三部曲”,是全球肝病科医生面临的巨大挑战。他汀类药物自问世以来,在心血管疾病和高脂血症治疗中发挥了巨大作用,近年来其同样显示出在慢性肝病中具有改善肝脂肪变性、抗炎、调节肝星状细胞表型、降低门静脉压力、改善肝脏微循环等关键环节的重要潜力。本文综述了他汀类药物在慢性肝病基础和临床研究中的最新进展,为慢性肝病的研究和防治提供新的见解。

     

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  • 收稿日期:  2024-02-18
  • 录用日期:  2024-04-17
  • 出版日期:  2024-10-25
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