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非酒精性脂肪性肝病相关肝细胞癌的研究进展

辜雪莲 李俊峰 毛小荣

引用本文:
Citation:

非酒精性脂肪性肝病相关肝细胞癌的研究进展

DOI: 10.3969/j.issn.1001-5256.2022.01.034
基金项目: 

国家自然科学基金 (81800528);

甘肃省自然科学基金 (20JR5RA364);

甘肃省重点研发计划 (20YF2FA011);

甘肃省卫生行业科研计划项目 (GSWSKY2018-24)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:辜雪莲负责撰写论文; 李俊峰修改论文; 毛小荣负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    毛小荣,mxr2013@126.com

Research advances in nonalcoholic fatty liver disease-related hepatocellular carcinoma

Research funding: 

National Natural Science Foundation (81800528);

Gansu Provincial Natural Science Foundation (20JR5RA364);

Gansu Province Key Research and Development Plan (20YF2FA011);

Gansu Provincial Health Industry Research Project (GSWSKY2018-24)

  • 摘要: 非酒精性脂肪性肝病相关肝细胞癌发病率在世界范围内呈增长趋势,然而其发病机制仍不明确。结合近年文献,总结脂肪组织炎症、氧化应激、肠道菌群及胰岛素抵抗在非酒精性脂肪性肝病相关肝细胞癌发病过程中的作用,并针对以上机制的防治进展进行综述,为其治疗提供新思路。

     

  • 图  1  NAFLD相关HCC发病机制

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  • 收稿日期:  2021-06-04
  • 录用日期:  2021-08-17
  • 出版日期:  2022-01-20
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