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近二十年我国自身免疫性肝病领域发展历程的回顾与展望

闫惠平 刘燕敏 张海萍

引用本文:
Citation:

近二十年我国自身免疫性肝病领域发展历程的回顾与展望

DOI: 10.3969/j.issn.1001-5256.2022.04.001
基金项目: 

北京市属医学科研院所公益发展改革试点项目 (Jingyiyan 2021-10);

首都医科大学附属北京佑安医院2021年院内中青年人才孵育项目(青年创新类) (YNKTQN2021004)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:闫惠平负责论文设计、部分内容撰写及论文修改与定稿;刘燕敏负责部分内容的撰写;张海萍完成部分数据查询和制图等工作。
详细信息
    通信作者:

    闫惠平,yhp503@126.com

Review and prospect of the development in the field of autoimmune liver diseases in China over the last 20 years

Research funding: 

Pilot Project of Public Welfare Development and Reform of Beijing Municipal Medical Research Institutes (Jingyiyan 2021-10);

Young and Middle-aged Talent Incubation Project in the Hospital of Beijing YouAn Hospital, Capital Medical University, 2021 (Youth Innovation) (YNKTQN2021004)

More Information
    Corresponding author: YAN Huipng, yhp503@126.com(ORCID: 0000-0002-1787-0067)
  • 摘要: 本文通过大数据回顾了2001年—2020年我国自身免疫性肝病领域获得国家级研究项目和在国内外发表学术论文的情况,结果展现了二十年来的发展变化趋势。介绍了新发布的自身免疫性肝病诊断治疗指南的更新要点,回顾了自身抗体检测技术的发展并分析其进展。

     

  • 图  1  我国学者2001年—2020年获批AILD相关国家自然科学基金项目的变化趋势

    Figure  1.  Changes in the number of AILD-related projects of National Natural Science Foundationof China for Chinese scholars from 2001 to 2020

    图  2  我国学者2001年—2020年间在国际期刊发表AILD相关论文变化趋势

    Figure  2.  Changes in the number of AILD-related papers published by Chinese scholars in international journals from 2001 to 2020

    图  3  我国学者2001年—2020年间在国际期刊发表AIH相关论文数量变化趋势

    Figure  3.  Changes in the number of AIH-related papers published by Chinese scholars in international journals from 2001 to 2020

    图  4  我国学者2001年—2020年间在国际期刊发表PBC相关论文数量变化趋势

    Figure  4.  Changes in the number of PBC-related papers published by Chinese scholars in international journals from 2001 to 2020

    图  5  我国学者2001年—2020年间在国内期刊发表AILD相关论文变化趋势

    Figure  5.  Changes in the number of AILD-related papers published by Chinese scholars in domestic journals from 2001 to 2020

  • [1] The Committee of the Autoantibodies Detection of Rheumatology and Immunology Physicians Committee of Chinese Medical Doctor Association. Expert consensus on clinical application of autoantibodies detection in patients with autoimmune liver disease[J]. Chin J Intern Med, 2021, 60(7): 619-625. DOI: 10.3760/cma.j.cn112138-20210114-00037.

    中国医师协会风湿免疫科医师分会自身抗体检测专业委员会. 自身免疫性肝病相关自身抗体检测的临床应用专家共识[J]. 中华内科杂志, 2021, 60(7): 619-625. DOI: 10.3760/cma.j.cn112138-20210114-00037.
    [2] ALVAREZ F, BERG PA. BIANCHI FB, et al. International Autoimmune Hepatitis Group Report: Review of criteria for diagnosis of autoimmune hepatitis[J]. J Hepatol, 1999, 31(5): 929-938. DOI: 10.1016/s0168-8278(99)80297-9.
    [3] GALASKI J, CHRISTINA WN, SCHAKAT M, et al. Update of the simplified criteria for autoimmune hepatitis: Evaluation of the methodology for immunoserological testing[J]. J Hepatol, 2021, 74(2): 312-320. DOI: 10.1016/j.jhep.2020.07.032.
    [4] YAN HP, LIU YM, ZHANG HP. Introduction to 2015 International Symposium on Autoimmune Liver Disease[J]. Chin J Hepatol, 2015, 23(8): 32-35. DOI: 10.3760/cma.j.issn.1007-3418.2015.10.000.

    闫惠平, 刘燕敏, 张海萍. 2015年肝脏自身免疫疾病国际会议简介[J]. 中华肝脏病杂志, 2015, 23(8): 32-35. DOI: 10.3760/cma.j.issn.1007-3418.2015.10.000.
    [5] Chinese Society of Hepatology, Chinese Medical Association. Guidelines on the diagnosis and management of autoimmune hepatitis (2021)[J]. J Clin Hepatol, 2022, 38(1): 42-49. DOI: 10.3760/cma.j.cn112138-20211112-00796.

    中华医学会肝病学分会. 自身免疫性肝炎诊断和治疗指南(2021)[J]. 临床肝胆病杂志, 2022, 38(1): 42-49. DOI: 10.3760/cma.j.cn112138-20211112-00796.
    [6] Chinese Society of Hepatology, Chinese Medical Association. Guidelines on the diagnosis and management of primary biliary cholangitis (2021)[J]. J Clin Hepatol, 2022, 38(1): 35-41. DOI: 10.3760/cma.j.cn112138-20211112-00794.

    中华医学会肝病学分会. 原发性胆汁性胆管炎的诊断和治疗指南(2021)[J]. 临床肝胆病杂志, 2022, 38(1): 35-41. DOI: 10.3760/cma.j.cn112138-20211112-00794.
    [7] Chinese Society of Hepatology, Chinese Medical Association. Guidelines on the diagnosis and management of primary sclerosing cholangitis (2021)[J]. J Clin Hepatol, 2022, 38(1): 50-61. DOI: 10.3760/cma.j.cn112138-20211109-00786.

    中华医学会肝病学分会. 原发性硬化性胆管炎诊断及治疗指南(2021)[J]. 临床肝胆病杂志, 2022, 38(1): 50-61. DOI: 10.3760/cma.j.cn112138-20211109-00786.
    [8] European Association for the Study of the Liver. EASL Autoimmune hepatitis Clinical Practice Guideline[J]. J Hepatol, 2015, 63(4): 971-1004. DOI: 10.1016/j.jhep.2015.06.030.
    [9] LINDOR KD, BOWLUS CL, BOYER J, et al. Primary Biliary Cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases[J]. Hepatology, 2021. DOI: 10.1002/hep.32117.[Online ahead of print]
    [10] SHEN F, ZHANG HP, WANG J, et al. Detection of autoimmune liver disease related autoantibodies: A report from 2012-2018 national wide survey[J]. Chin J Rheumatol, 2020, 24(11): 736-742. DOI: 10.3760/cma.j.c141217-20200205-00041.

    沈芳, 张海萍, 王晶, 等. 2016-2018年全国自身免疫性肝病相关自身抗体检测质量调查评价[J]. 中华风湿病学杂志, 2020, 24(11): 736-742. DOI: 10.3760/cma.j.c141217-20200205-00041.
    [11] ZHONG RQ, YANG ZX. New era in autoantibodies detection: quantitation[J]. Chin J Lab Med, 2014, 37(8): 561-563. DOI: 10.3760/cma.j.issn.1009-9158.2014.08.001.

    仲人前, 杨再兴. 自身抗体检测进入定量检测时代[J]. 中华检验医学杂志, 2014, 37(8): 561-563. DOI: 10.3760/cma.j.issn.1009-9158.2014.08.001.
    [12] European Association for the Study of the Liver. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis[J]. J Hepatology, 2017, 67(1): 145-172. DOI: 10.1016/j.jhep.2017.03.022.
    [13] WEI Y, LI Y, YAN L, et al. Alterations of gut microbiome in autoimmune hepatitis[J]. Gut, 2020, 69(3): 569-577. DOI: 10.1136/gutjnl-2018-317836.
    [14] CZAJA AJ. Examining pathogenic concepts of autoimmune hepatitis for cues to future investigations and interventions[J]. World J Gastroenterol, 2019, 25(45): 6579- 6606. DOI: 10.3748/wjg.v25.i45.6579
    [15] WANG L, HAN Y. Diagnosis and treatment of primary biliary cholangitis: Current status and challenges[J]. J Clin Hepatol, 2021, 37(10): 2257-2261. DOI: 10.3969/j.issn.1001-5256.2021.10.001.
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  • 收稿日期:  2022-01-04
  • 录用日期:  2022-02-07
  • 出版日期:  2022-04-20
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