中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

数字疗法在非酒精性脂肪性肝病治疗中的应用

孙超 范建高

引用本文:
Citation:

数字疗法在非酒精性脂肪性肝病治疗中的应用

DOI: 10.3969/j.issn.1001-5256.2022.04.032
基金项目: 

国家自然科学基金 (81000173);

国家自然科学基金 (81873565);

新华医院院级临床研究项目 (17CSK04);

新华医院院级临床研究项目 (15LC06)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:孙超负责查阅文章,撰写论文; 范建高负责修改文章并最后定稿。
详细信息
    通信作者:

    范建高,fattyliver2004@126.com

Application of digital therapeutics in the treatment of nonalcoholic fatty liver disease

Research funding: 

National Natural Science Foundation of China (81000173);

National Natural Science Foundation of China (81873565);

Hospital Funded Clinical Research, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine (17CSK04);

Hospital Funded Clinical Research, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine (15LC06)

More Information
  • 摘要: 非酒精性脂肪性肝病(NAFLD)已成为全球第一大慢性肝病,严重危害人类健康。迄今为止,改变不良的生活方式仍是最重要的NAFLD治疗措施。然而,传统生活方式干预依赖于医院复诊随访,患者执行力和依从性差,而借助互联网技术的数字疗法可克服这些弊端,在NAFLD患者中的应用初见成效。本文概述了数字疗法在医学和NAFLD治疗中的应用,旨在为NAFLD的治疗提供借鉴。

     

  • [1] National Workshop on Fatty Liver and Alcoholic Liver Disease, Chinese Society of Hepatology, Chinese Medical Association, Fatty Liver Expert Committee, Chinese Medical Doctor Association. Guidelines of prevention and treatment for nonalcoholic fatty liver disease: A 2018 update[J]. J Clin Hepatol, 2018, 34(5): 947-957. DOI: 10.3969/j.issn.1001-5256.2018.05.007.

    中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会. 非酒精性脂肪性肝病防治指南(2018年更新版)[J]. 临床肝胆病杂志, 2018, 34(5): 947-957. DOI: 10.3969/j.issn.1001-5256.2018.05.007.
    [2] GEPNER Y, SHELEF I, SCHWARZFUCHS D, et al. Effect of distinct lifestyle interventions on mobilization of fat storage pools: CENTRAL magnetic resonance imaging randomized controlled trial[J]. Circulation, 2018, 137(11): 1143-1157. DOI: 10.1161/CIRCULATIONAHA.117.030501.
    [3] ROMÁN E, GARCÍA-GALCERÁN C, TORRADES T, et al. Effects of an exercise programme on functional capacity, body composition and risk of falls in patients with cirrhosis: A randomized clinical trial[J]. PLoS One, 2016, 11(3): e0151652. DOI: 10.1371/journal.pone.0151652.
    [4] ZHANG HJ, HE J, PAN LL, et al. Effects of moderate and vigorous exercise on nonalcoholic fatty liver disease: A randomized clinical trial[J]. JAMA Intern Med, 2016, 176(8): 1074-1082. DOI: 10.1001/jamainternmed.2016.3202.
    [5] ABDELBASSET WK, TANTAWY SA, KAMEL DM, et al. A randomized controlled trial on the effectiveness of 8-week high-intensity interval exercise on intrahepatic triglycerides, visceral lipids, and health-related quality of life in diabetic obese patients with nonalcoholic fatty liver disease[J]. Medicine (Baltimore), 2019, 98(12): e14918. DOI: 10.1097/MD.0000000000014918.
    [6] WONG VW, WONG GL, CHAN RS, et al. Beneficial effects of lifestyle intervention in non-obese patients with non-alcoholic fatty liver disease[J]. J Hepatol, 2018, 69(6): 1349-1356. DOI: 10.1016/j.jhep.2018.08.011.
    [7] MORI H, TOKUDA Y. Effect of whey protein supplementation after resistance exercise on the muscle mass and physical function of healthy older women: A randomized controlled trial[J]. Geriatr Gerontol Int, 2018, 18(9): 1398-1404. DOI: 10.1111/ggi.13499.
    [8] GALBREATH M, CAMPBELL B, LABOUNTY P, et al. Effects of adherence to a higher protein diet on weight loss, markers of health, and functional capacity in older women participating in a resistance-based exercise program[J]. Nutrients, 2018, 10(8): E1070. DOI: 10.3390/nu10081070.
    [9] MERCHANT R, INAMDAR R, HENDERSON K, et al. Digital health intervention for asthma: Patient-reported value and usability[J]. JMIR Mhealth Uhealth, 2018, 6(6): e133. DOI: 10.2196/mhealth.7362.
    [10] RASSOULI F, BOUTELLIER D, DUSS J, et al. Digitalizing multidisciplinary pulmonary rehabilitation in COPD with a smartphone application: An international observational pilot study[J]. Int J Chron Obstruct Pulmon Dis, 2018, 13: 3831-3836. DOI: 10.2147/COPD.S182880.
    [11] MORIN CM. Profile of Somryst prescription digital therapeutic for chronic insomnia: Overview of safety and efficacy[J]. Expert Rev Med Devices, 2020, 17(12): 1239-1248. DOI: 10.1080/17434440.2020.1852929.
    [12] HENDRICKS TM, GUTIERREZ CN, STULAK JM, et al. The use of virtual reality to reduce preoperative anxiety in first-time sternotomy patients: A randomized controlled pilot trial[J]. Mayo Clin Proc, 2020, 95(6): 1148-1157. DOI: 10.1016/j.mayocp.2020.02.032.
    [13] PETRONI ML, BRODOSI L, BARBANTI FA, et al. Lifestyle changes for the treatment of nonalcoholic fatty liver disease-a 2015-19 update[J]. Curr Pharm Des, 2020, 26(10): 1110-1118. DOI: 10.2174/1381612826666200204095401.
    [14] MAZZOTTI A, CALETTI MT, BRODOSI L, et al. An internet-based approach for lifestyle changes in patients with NAFLD: Two-year effects on weight loss and surrogate markers[J]. J Hepatol, 2018, 69(5): 1155-1163. DOI: 10.1016/j.jhep.2018.07.013.
    [15] PFIRRMANN D, HUBER Y, SCHATTENBERG JM, et al. Web-based exercise as an effective complementary treatment for patients with nonalcoholic fatty liver disease: Intervention study[J]. J Med Internet Res, 2019, 21(1): e11250. DOI: 10.2196/11250.
    [16] HUBER Y, PFIRRMANN D, GEBHARDT I, et al. Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program[J]. Aliment Pharmacol Ther, 2019, 50(8): 930-939. DOI: 10.1111/apt.15427.
    [17] LIM SL, JOHAL J, ONG KW, et al. Lifestyle intervention enabled by mobile technology on weight loss in patients with nonalcoholic fatty liver disease: Randomized controlled trial[J]. JMIR Mhealth Uhealth, 2020, 8(4): e14802. DOI: 10.2196/14802.
    [18] TINCOPA MA, LYDEN A, WONG J, et al. Impact of a pilot structured mobile technology based lifestyle intervention for patients with nonalcoholic fatty liver disease[J]. Dig Dis Sci, 2021: 1-11. DOI: 10.1007/s10620-021-06922-6.
    [19] SASLOW LR, MASON AE, KIM S, et al. An online intervention comparing a very low-carbohydrate ketogenic diet and lifestyle recommendations versus a plate method diet in overweight individuals with type 2 diabetes: A randomized controlled trial[J]. J Med Internet Res, 2017, 19(2): e36. DOI: 10.2196/jmir.5806.
    [20] LIANG G, JIANG H, HUANG C, et al. Diabetes health management strategy based on internet plus graded diagnosis and treatment strategy[J]. Ann Palliat Med, 2020, 9(6): 3915-3922. DOI: 10.21037/apm-20-1996.
    [21] ZAHARIA OP, KUPRIYANOVA Y, KARUSHEVA Y, et al. Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: A feasibility study[J]. Eur J Nutr, 2021, 60(7): 3811-3818. DOI: 10.1007/s00394-021-02521-3.
  • 加载中
计量
  • 文章访问数:  760
  • HTML全文浏览量:  252
  • PDF下载量:  151
  • 被引次数: 0
出版历程
  • 收稿日期:  2021-08-04
  • 出版日期:  2022-04-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回