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对熊去氧胆酸应答不佳或不耐受的原发性胆汁性胆管炎患者应用奥贝胆酸和贝特类药物治疗的研究进展

帅俊芳 韩子岩

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对熊去氧胆酸应答不佳或不耐受的原发性胆汁性胆管炎患者应用奥贝胆酸和贝特类药物治疗的研究进展

DOI: 10.3969/j.issn.1001-5256.2022.04.035
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:帅俊芳负责课题设计,查阅文献,撰写文章; 韩子岩负责指导、修改文章。
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    韩子岩,rweiliaoshi@126.com

Research advances in obeticholic acid and fibrates in treatment of primary biliary cholangitis with poor response or intolerance to ursodeoxycholic acid

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  • 摘要: 熊去氧胆酸治疗原发性胆汁性胆管炎会发生应答不佳或不耐受,更换为奥贝胆酸或贝特类单药或联合治疗后,部分治疗方案也会出现应答不佳或不耐受。近年奥贝胆酸和贝特类药物临床研究逐步解决这些问题,奥贝胆酸/贝特类药物与熊去氧胆酸的联合治疗对非晚期肝硬化原发性胆汁性胆管炎患者是有效和安全的。

     

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  • 收稿日期:  2021-08-04
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