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戊型肝炎病毒跨种间传播研究进展

李云龙 黄芬

引用本文:
Citation:

戊型肝炎病毒跨种间传播研究进展

DOI: 10.3969/j.issn.1001-5256.2023.11.004
基金项目: 

‍国家自然科学基金 (82260396)

云南省杰出青年项目 (202001AV070005)

云南高校病毒感染与生殖损伤科技创新团队资助项目 (2020)

利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:‍李云龙负责设计论文框架,起草论文;黄芬负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    ‍黄芬, huangfen6789@163.com (ORCID: 0000-0001-9147-2537)

Research advances in the interspecies transmission of hepatitis E virus

Research funding: 

‍National Natural Science Foundation of China (82260396);

Natural Science Foundation for Distinguished Young Scholars of Yunnan Province (202001AV070005);

Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province (2020)

More Information
  • 摘要: 戊型肝炎病毒(HEV)是病毒性肝炎的病原体,可经动物跨种间传播,其感染导致的戊型肝炎发病率居世界急性病毒性肝炎的首位,现已成为危害人类健康的主要公共健康问题。近年来,越来越多的物种被鉴定成为HEV新的天然宿主,HEV跨种间传播途径越来越多,严重阻碍了对该病毒的防控。因此,本文旨在总结、探讨HEV跨物种间传播的进展,为防控HEV的传播提供参考。

     

  • [1] SAYED IM, VERCOUTER AS, ABDELWAHAB SF, et al. Is hepatitis E virus an emerging problem in industrialized countries?[J]. Hepatology, 2015, 62( 6): 1883- 1892. DOI: 10.1002/hep.27990.
    [2] Chinese Society of Hepatology, Chinese Medical Association. Consensus on prevention and treatment of hepatitis E[J]. Chin J Hepatol, 30( 8): 820- 831. DOI: 10.3760/cma.j.cn501113-20220729-00401.

    中华医学会肝病学分会. 戊型肝炎防治共识[J]. 中华肝脏病杂志, 30( 8): 820- 831. DOI: 10.3760/cma.j.cn501113-20220729-00401.
    [3] LI PF, LIU JY, LI Y, et al. The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis[J]. Liver Int, 2020, 40( 7): 1516- 1528. DOI: 10.1111/liv.14468.
    [4] PATRA S, KUMAR A, TRIVEDI SS, et al. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection[J]. Ann Intern Med, 2007, 147( 1): 28. DOI: 10.7326/0003-4819-147-1-200707030-00005.
    [5] KAMAR N, GARROUSTE C, HAAGSMA EB, et al. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants[J]. Gastroenterology, 2011, 140( 5): 1481- 1489. DOI: 10.1053/j.gastro.2011.02.050.
    [6] Chinese Consortium for the Study of Hepatitis E(CCSHE), Chinese Physician Association for Infectious Disease, National Clinical Research Center for Infectious Diseases. Expert consensus on the process of in-hospital screening and management of viral hepatitis E in China(2023)[J]. J Clin Hepatol, 2023, 39( 4): 785- 794. DOI: 10.3969/j.issn.1001-5256.2023.04.008.

    中国戊型肝炎研究协助组(CCSHE), 中国医师协会感染科医师分会, 国家感染性疾病临床医学研究中心. 中国戊型病毒性肝炎院内筛查管理流程专家共识(2023年版)[J]. 临床肝胆病杂志, 2023, 39( 4): 785- 794. DOI: 10.3969/j.issn.1001-5256.2023.04.008.
    [7] European Association for The Study of The Liver. EASL Clinical Practice Guidelines on hepatitis E virus infection[J]. J Hepatol, 2018, 68( 6): 1256- 1271. DOI: 10.1016/j.jhep.2018.03.005.
    [8] NIMGAONKAR I, DING Q, SCHWARTZ RE, et al. Hepatitis E virus: Advances and challenges[J]. Nat Rev Gastroenterol Hepatol, 2018, 15( 2): 96- 110. DOI: 10.1038/nrgastro.2017.150.
    [9] MENG XJ, PURCELL RH, HALBUR PG, et al. A novel virus in swine is closely related to the human hepatitis E virus[J]. Proc Natl Acad Sci USA, 1997, 94( 18): 9860- 9865. DOI: 10.1073/pnas.94.18.9860.
    [10] PAVIO N, DOCEUL V, BAGDASSARIAN E, et al. Recent knowledge on hepatitis E virus in Suidae Reservoirs and transmission routes to human[J]. Vet Res, 2017, 48( 1): 78. DOI: 10.1186/s13567-017-0483-9.
    [11] TAKAHASHI H, TANAKA T, JIRINTAI S, et al. A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus(HEV) strains: Demonstration of HEV infectivity of porcine liver sold as food[J]. Arch Virol, 2012, 157( 2): 235- 246. DOI: 10.1007/s00705-011-1153-2.
    [12] WIDÉN F, SUNDQVIST L, MATYI-TOTH A, et al. Molecular epidemiology of hepatitis E virus in humans, pigs and wild boars in Sweden[J]. Epidemiol Infect, 2011, 139( 3): 361- 371. DOI: 10.1017/S0950268810001342.
    [13] ROSE N, LUNAZZI A, DORENLOR V, et al. High prevalence of Hepatitis E virus in French domestic pigs[J]. Comp Immunol Microbiol Infect Dis, 2011, 34( 5): 419- 427. DOI: 10.1016/j.cimid.2011.07.003.
    [14] PAVIO N, MERBAH T, THÉBAULT A. Frequent hepatitis E virus contamination in food containing raw pork liver, France[J]. Emerg Infect Dis, 2014, 20( 11): 1925- 1927. DOI: 10.3201/eid2011.140891.
    [15] BOUWKNEGT M, LODDER-VERSCHOOR F, VAN DER POEL WHM, et al. Hepatitis E virus RNA in commercial porcine livers in The Netherlands[J]. J Food Prot, 2007, 70( 12): 2889- 2895. DOI: 10.4315/0362-028x-70.12.2889.
    [16] SATO Y, SATO H, NAKA K, et al. A nationwide survey of hepatitis E virus(HEV) infection in wild boars in Japan: Identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes[J]. Arch Virol, 2011, 156( 8): 1345- 1358. DOI: 10.1007/s00705-011-0988-x.
    [17] TEI S, KITAJIMA N, TAKAHASHI K, et al. Zoonotic transmission of hepatitis E virus from Deer to human beings[J]. Lancet, 2003, 362( 9381): 371- 373. DOI: 10.1016/S0140-6736(03)14025-1.
    [18] ANHEYER-BEHMENBURG HE, SZABO K, SCHOTTE U, et al. Hepatitis E virus in wild boars and spillover infection in red and roe Deer, Germany, 2013-2015[J]. Emerg Infect Dis, 2017, 23( 1): 130- 133. DOI: 10.3201/eid2301.161169.
    [19] GO HJ, PARK BJ, AHN HS, et al. Identification of hepatitis E virus in bovine and porcine raw livers[J]. J Microbiol Biotechnol, 2019, 29( 12): 2022- 2025. DOI: 10.4014/jmb.1910.10059.
    [20] LI S, LIU MX, CONG JJ, et al. Detection and characterization of hepatitis E virus in goats at slaughterhouse in Tai’an region, China[J]. Biomed Res Int, 2017, 2017: 3723650. DOI: 10.1155/2017/3723650.
    [21] WU JY, SI FS, JIANG CY, et al. Molecular detection of hepatitis E virus in sheep from southern Xinjiang, China[J]. Virus Genes, 2015, 50( 3): 410- 417. DOI: 10.1007/s11262-015-1194-9.
    [22] HUANG F, LI YL, YU WH, et al. Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis[J]. Hepatology, 2016, 64( 2): 350- 359. DOI: 10.1002/hep.28668.
    [23] TREAGUS S, WRIGHT C, BAKER-AUSTIN C, et al. The foodborne transmission of hepatitis E virus to humans[J]. Food Environ Virol, 2021, 13( 2): 127- 145. DOI: 10.1007/s12560-021-09461-5.
    [24] LI TC, ZHOU XF, YOSHIZAKI S, et al. Production of infectious dromedary camel hepatitis E virus by a reverse genetic system: Potential for zoonotic infection[J]. J Hepatol, 2016, 65( 6): 1104- 1111. DOI: 10.1016/j.jhep.2016.07.013.
    [25] WANG L, TENG JLL, LAU SKP, et al. Transmission of a novel genotype of hepatitis E virus from Bactrian camels to Cynomolgus macaques[J]. J Virol, 2019, 93( 7): e02014- e02018. DOI: 10.1128/JVI.02014-18.
    [26] DEMIRCI M, YIĞIN A, ÜNLÜ Ö, et al. Detection of HEV RNA amounts and genotypes in raw milks obtained from different animals[J]. Mikrobiyol Bul, 2019, 53( 1): 43- 52. DOI: 10.5578/mb.67468.
    [27] EL-MOKHTAR MA, ELKHAWAGA AA, SAYED IM. Assessment of hepatitis E virus(HEV) in the edible goat products pointed out a risk for human infection in Upper Egypt[J]. Int J Food Microbiol, 2020, 330: 108784. DOI: 10.1016/j.ijfoodmicro.2020.108784.
    [28] MESQUITA JR, SANTOS-FERREIRA N, FERREIRA AS, et al. Increased risk of hepatitis E virus infection in workers occupationally exposed to sheep[J]. Transbound Emerg Dis, 2020. DOI: 10.1111/tbed.13524.
    [29] SAYED IM, ELKHAWAGA AA, EL-MOKHTAR MA. Circulation of hepatitis E virus(HEV) and/or HEV-like agent in non-mixed dairy farms could represent a potential source of infection for Egyptian people[J]. Int J Food Microbiol, 2020, 317: 108479. DOI: 10.1016/j.ijfoodmicro.2019.108479.
    [30] PURCELL RH, ENGLE RE, ROOD MP, et al. Hepatitis E virus in rats, los angeles, California, USA[J]. Emerg Infect Dis, 2011, 17( 12): 2216- 2222. DOI: 10.3201/eid1712.110482.
    [31] World Health Organization. Global hepatitis report, 2017[OR/OL]. http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/. http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/
    [32] REUTER G, BOROS Á, PANKOVICS P. Review of hepatitis E virus in rats: Evident risk of species Orthohepevirus C to human zoonotic infection and disease[J]. Viruses, 2020, 12( 10): 1148. DOI: 10.3390/v12101148.
    [33] WANG B, HARMS D, YANG XL, et al. Orthohepevirus C: An expanding species of emerging hepatitis E virus variants[J]. Pathogens, 2020, 9( 3): 154. DOI: 10.3390/pathogens9030154.
    [34] ABRAVANEL F, LHOMME S, COSTA H EL, et al. Rabbit hepatitis E virus infections in humans, France[J]. Emerg Infect Dis, 2017, 23( 7): 1191- 1193. DOI: 10.3201/eid2307.170318.
    [35] PRIMADHARSINI PP, NAGASHIMA S, OKAMOTO H. Mechanism of cross-species transmission, adaptive evolution and pathogenesis of hepatitis E virus[J]. Viruses, 2021, 13( 5): 909. DOI: 10.3390/v13050909.
    [36] LIANG HB, CHEN JD, XIE JX, et al. Hepatitis E virus serosurvey among pet dogs and cats in several developed cities in China[J]. PLoS One, 2014, 9( 6): e98068. DOI: 10.1371/journal.pone.0098068.
    [37] LI YL, QU CB, SPEE B, et al. Hepatitis E virus seroprevalence in pets in the Netherlands and the permissiveness of canine liver cells to the infection[J]. Ir Vet J, 2020, 73: 6. DOI: 10.1186/s13620-020-00158-y.
    [38] ZENG MY, GAO H, YAN XX, et al. High hepatitis E virus antibody positive rates in dogs and humans exposed to dogs in the south-west of China[J]. Zoonoses Public Health, 2017, 64( 8): 684- 688. DOI: 10.1111/zph.12377.
    [39] SONG YJ, JEONG HJ, KIM YJ, et al. Analysis of complete genome sequences of swine hepatitis E virus and possible risk factors for transmission of HEV to humans in Korea[J]. J Med Virol, 2010, 82( 4): 583- 591. DOI: 10.1002/jmv.21730.
    [40] RIVADULLA E, VARELA MF, MESQUITA JR, et al. Detection of hepatitis E virus in shellfish harvesting areas from Galicia(northwestern Spain)[J]. Viruses, 2019, 11( 7): 618. DOI: 10.3390/v11070618.
    [41] WARREN CJ, SAWYER SL. How host genetics dictates successful viral zoonosis[J]. PLoS Biol, 2019, 17( 4): e3000217. DOI: 10.1371/journal.pbio.3000217.
    [42] SHUKLA P, NGUYEN HT, TORIAN U, et al. Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant[J]. Proc Natl Acad Sci USA, 2011, 108( 6): 2438- 2443. DOI: 10.1073/pnas.1018878108.
    [43] DALTON HR, BENDALL RP, KEANE FE, et al. Persistent carriage of hepatitis E virus in patients with HIV infection[J]. N Engl J Med, 2009, 361( 10): 1025- 1027. DOI: 10.1056/NEJMc0903778.
    [44] FEAGINS AR, CÓRDOBA L, SANFORD BJ, et al. Intergenotypic chimeric hepatitis E viruses(HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs[J]. Virus Res, 2011, 156( 1-2): 141- 146. DOI: 10.1016/j.virusres.2010.12.011.
    [45] BOUQUET J, CHEREL P, PAVIO N. Genetic characterization and codon usage bias of full-length Hepatitis E virus sequences shed new lights on genotypic distribution, host restriction and genome evolution[J]. Infect Genet Evol, 2012, 12( 8): 1842- 1853. DOI: 10.1016/j.meegid.2012.07.021.
    [46] ZHOU JH, LI XR, LAN X, et al. The genetic divergences of codon usage shed new lights on transmission of hepatitis E virus from swine to human[J]. Infect Genet Evol, 2019, 68: 23- 29. DOI: 10.1016/j.meegid.2018.11.024.
    [47] BAHA S, BEHLOUL N, LIU ZZ, et al. Comprehensive analysis of genetic and evolutionary features of the hepatitis E virus[J]. BMC Genomics, 2019, 20( 1): 790. DOI: 10.1186/s12864-019-6100-8.
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  • 收稿日期:  2023-04-23
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  • 出版日期:  2023-11-28
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